Publications

2021 – Present

• Lynch RM, Bar KJ. Development of screening assays for use of broadly neutralizing antibodies in people with HIV. Curr Opin HIV AIDS. 2023 Jul 1;18(4):171-177.

• Tebas P, Lynn K, Azzoni L, Cocchella G, Papasavvas E, Fair M, Karanam B, Sharma P, Reeves JD, Petropoulos CJ, Lalley-Chareczko L, Kostman JR, Short W, Mounzer K, Montaner LJ. Susceptibility to 3BNC117 and 10-1074 in ART suppressed chronically infected persons. AIDS. 2023 Jul 1; 37(8):p 1203-1207.

• Campbell CK, Dubé K, Sauceda JA, Sevelius JM, Green-Ajufo B, Brown B, Ndukwe S, Saberi P. Cash Transfer Apps are a Feasible, Acceptable, and More Equitable Method for Compensating Participants in HIV Research. J Acquir Immune Defic Syndr. 2023 Jul 1;93(3):e9-e11.

• Joshi LR, Gálvez NMS, Ghosh S, Weiner DB, Balazs AB. Delivery platforms for broadly neutralizing antibodies. Curr Opin HIV AIDS. 2023 Jul 1;18(4):191-208.

• Sanders-Beer BE, Archin NM, Brumme ZL, Busch M, Deleage C, O’Doherty U, Hughes SH, Jerome K, Jones RB, Karn J, Kearney MF, Keele B, Kulpa D, Laird G, Li JZ, Lichterfeld M, Nussenzweig MC, Persaud D, Yukl S, Siliciano RF, Mellors JW. Current HIV/SIV Reservoir Assays for Preclinical and Clinical Applications: Recommendations from the Experts 2022 NIAID Workshop Summary. AIDS Res Hum Retroviruses. 2023 Jun 19. Doi: 10.1089/AID.2022.00188.

• Dubé K, Peterson B, Jones NL, Onorato A, Carter WB, Dannaway C, Johnson S, Hayes R, Hill M, Maddox R, Riley JL, Shull J, Metzger D, Montaner LJ. Community engagement group model in basic and biomedical research: lessons learned from the BEAT-HIV Delaney Collaboratory towards an HIV-1 cure. Res Involv Engagem. 2023 Jun 8;9(1):39.

• Marquis KA, Everett J, Cantu A, McFarland A, Sherrill-Mix S, Krystal M, Parcella K, Gillis E, Fridell RA, Bushman FD. The HIV-1 Capsid-Targeted Inhibitor GSK878 Alters Selection of Target Sites for HIV DNA Integration. AIDS Res Hum Retroviruses. 2023 Jun 7. Doi: 10.1089/AID.2022.0161. Online ahead of print.

• Dubé K, Morton T, Fox L, Dee L, Palm D, Villa TJ, Freshwater W, Taylor J, Graham G, Carter WB, Sauceda JA, Peluso MJ, Rid A. A partner protection package for HIV cure-related trials involving analytical treatment interruptions. Lancet Infect Dis. 2023 Jun 6:S1473-3099(23)00267-0.

• Dubé K, Villa TJ, Taylor J, Kaytes A, Moore DJ, Little SJ, Chaillon A, Smith DM, Gianella S. A Community-Driven Framework to Prioritize the Use of Donated Human Biological Materials in the Context of HIV Cure-Related Research at the End of Life. Pathog Immun. 2023 May 24;8(1):1-16.

• Tietjen I, Schonhofer C, Sciorillo A, Naidu ME, Haq Z, Kannan T, Kossenkov AV, Rivera-Ortiz J, Mounzer K, Hart C, Gyampoh K, Yuan Z, Beattie KD, Rali T, Shuda McGuire K, Davis RA, Montaner LJ. The Natural Stilbenoid (-)-Hopeaphenol Inhibits HIV Transcription by Targeting Both PKC and NF-κB Signaling and Cyclin-Dependent Kinase 9. Antimicrob Agents Chemother. 2023 Apr 18;67(4):e0160022.

• White JA, Wu F, Yasin S, Moskovljevic M, Varriale J, Dragoni F, Camilo Contreras A, Duan J, Zheng MY, Tadzong NF, Patel HB, Quiambao JMC, Rhodehouse K, Zhang H, Lai J, Beg SA, Delannoy M, Kilcrease C, Hoffmann CJ, Poulin S, Chano F, Tremblay C, Cherian J, Barditch-Crovo P, Chida N, Moore RD, Summers MF, Siliciano RF, Siliciano JD, Simonetti FR. Clonally expanded HIV-1 proviruses with 5′-Leader defects can give rise to nonsuppressible residual viremia. J Clin Invest. 2023 March 15. 133(6):e165245.

• Yuan Z, Giron L, Hart C, Gyampoh A, Koshy J, Hong KY, Niki T, Premeaux TA, Ndhlovu LC, Montaner LJ*, Abdel-Mohsen M.* Human galectin-9 promotes the expansion of HIV reservoirs in vivo in humanized mice. AIDS. 2023 Mar 15. 37(4): 571-577.

• Wu VH, Nguyen S, Nordin JML, Joy J, Mampe F, Tebas P, Montaner L.J, Bar KJ, Vella LA, Betts MR. Profound phenotypic and epigenetic heterogeneity of the HIV-1 infected CD4+ T cell reservoir. Nature Immunology. 2023 Feb. 24(2): 359-370.

• Thobakgale C, Jost S. Editorial: Innate immune responses in HIV controllers. Front Immunol. 2023 Feb 15;14:1159278.

• Sun W, Gao C, Hartana CA, Osborn MR, Einkauf KB, Lian X, Bone B, Bonheur N, Chun TW, Rosenberg ES, Walker BD, Yu XG, Lichterfeld M. Phenotypic signatures of immune selection in HIV-1 reservoir cells. Nature. 2023 Feb. 614(7947): 309-317.

• Woolley G, Mosher M, Kroll K, Jones R, Hueber B, Sugawara S, Manickam C, Terry K, Varner V, Lifton M, Ram D, Fennessey CM, Keele BF, Reeves RK. Natural Killer Cells Regulate Acute SIV Replication, Dissemination, and Inflammation, but Do Not Impact Independent Transmission Events. J Virol. 2023 Jan 31;97(1):e0151922.

• Lian X, Seiger KW, Parsons EM, Gao C, Sun W, Gladkov GT, Roseto IC, Einkauf KB, Osborn MR, Chevalier JM, Jiang C, Blackmer J, Carrington M, Rosenberg ES, Lederman MM, McMahon DK, Bosch RJ, Jacobson JM, Gandhi RT, Peluso MJ, Chun TW, Deeks SG, Yu XG, Lichterfeld M. Progressive transformation of the HIV-1 reservoir cell profile over two decades of antiviral therapy. Cell Host Microbe. 2023 Jan 11;31(1):83-96.e5.

• Laumaea A, Marchitto L, Ding S, Beaudoin-Bussières G, Prévost J, Gasser R, Chatterjee D, Gendron-Lepage G, Medjahed H, Chen HC, Smith AB 3rd, Ding H, Kappes JC, Hahn BH, Kirchhoff F, Richard J, Duerr R, Finzi A. Small CD4 mimetics sensitize HIV-1-infected macrophages to antibody-dependent cellular cytotoxicity. Cell Rep. 2023 Jan 10;42(1):111983.

• Wei Y, Ho Y-C. Interferon opens up: HIV-induced inflammation reconfigures 3D chromatin conformation and affects where HIV integrates. Mol Cell. 2022 Dec 15;82(24):4585-4587.

• Campbell DM, Cowlings PD, Tholanah M, Robinson MJ, Graham G, Aseru S, Dubé K, Cohn SE, Bar KJ, Connick E, Mngqbisa R, Scully EP, Stockman JK, Gianella S. A Community Call to Action to Prioritize Inclusion and Enrollment of Women in HIV Cure-related Research. J Acquir Immune Defic Syndr. 2022 Dec 15;91(5):e12-e14.

• Saini P, Adeniji OS, Abdel-Mohsen M. Inhibitory Siglec-sialic acid interactions in balancing immunological activation and tolerance during viral infections. EBioMedicine. 2022 Dec; 86:104354.

• Dubé K, Kanazawa J, Roebuck C, Johnson S, Carter WB, Dee L, Peterson B, Lynn KM, Lalley-Chareczko L, Hiserodt E, Kim S, Rosenbloom D, Evans BR, Anderson M, Hazuda DJ, Shipley L, Bateman K, Howell BJ, Mounzer K, Tebas P, Montaner LJ. “We are looking at the future right now”: Community acceptability of a home-based viral load test device in the context of HIV cure-related research with analytical treatment interruptions in the United States. HIV Research & Clinical Practice. 2022 December. 23(1): 120-135.

• Riggs PK, Chaillon A, Jiang G, Letendre SL, Tang Y, Taylor J, Kaytes A, Smith DM, Dubé K, Gianella S. Lessons for Understanding Central Nervous System HIV Reservoirs from the Last Gift Program. Curr HIV/AIDS Rep. 2022 Dec;19(6):566-579.

• Dubé K, Campbell CK, Eskaf S, Sauceda JA, Ndukwe S, Henley L, Persaud D, Deeks SG, Auerbach JD, Saberi P. Willingness of Racially Diverse Young Adults Living with HIV to Participate in HIV Cure Research: A Cross-Sectional Survey in the United States. AIDS Res Hum Retroviruses. 2022 Nov 10. Doi: 10.1089/AID.2022.0005.

• Anikeeva N, Steblyanko M, Kuri-Cervantes L, Buggert M, Betts MR, Sykulev Y. The immune synapses reveal aberrant functions of CD8 T cells during chronic HIV infection. Nat Commun. 2022 Oct 28;13(1):6436.

• Dai W, Wu F, McMyn N, Song B, Walker-Sperling VE, Varriale J, Zhang H, Barouch DH, Siliciano JD, Li W, Siliciano RF. Genome-wide CRISPR screens identify combinations of candidate latency reversing agents for targeting the latent HIV-1 reservoir. Sci Transl Med. 2022 Oct 19;14(667):eabh3351.

• Neergaard R, Jones N, Roebuck C, Rendle KA, Barbati Z, Peterson B, Tebas P, Mounzer KC, Metzger DS, Montaner LJ. “I know that I was a part of making a difference”: Participant motivations for joining a cure-directed HIV trial with an analytical treatment interruption. AIDS Research and Human Retroviruses. 2022 Sept 15. Doi: 10/1089/AID.2022.0040. Online ahead of print.

• Dubé K, Agarwal H, Stockman JK, Auerbach JD, Sauceda JA, Conroy AA, Johnson MO. “I Would Absolutely Need to Know That My Partner Is Still Going to be Protected”: Perceptions of HIV Cure-Related Research Among Diverse HIV Serodifferent Couples in the United States. AIDS Res Hum Retroviruses. 2022 Sep 8. Doi: 10.1089/AID.2022.0036. Online ahead of print.

• Addison MM, Ellis GI, Leslie GJ, Zawadzky NB, Riley JL, Hoxie JA, Eisenlohr LC. HIV-1-Infected CD4+ T Cells Present MHC Class II-Restricted Epitope via Endogenous Processing. J Immunol. 2022 Sep 1;209(5):864-873.

• Jost S. Holding back: HLA-associated inhibition of NK cells gives HIV a leg up. Cell Host Microbe. 2022 Aug 10;30(8):1072-1073.

• Dubé K, Agarwal H, Carter WB, Dee L, Taylor J, Roebuck C, Peterson B, Patel H, Ndukwe S, Lynn KM, Lalley-Chareczko L, Hiserodt E, Kim S, Rosenbloom D, Evans BR, Anderson M, Hazuda DJ, Bateman K, Howell BJ, Azzoni L, Mounzer K, Tebas P, Montaner LJ. Participant experiences using novel home-based blood collection device for viral load testing in the context of HIV cure trials with analytical treatment interruptions. HIV Research & Clinical Practice. 2022 Aug 2. 23(1):76-90.

• Lichterfeld M, Gao C, Yu XG. An ordeal that does not heal: understanding barriers to a cure for HIV-1 infection. Trends Immunol. 2022 Aug;43(8):608-616.

• Pedersen SF, Collora JA, Kim RN, Yang K, Razmi A, Catalano AA, Yeh YJ, Mounzer K, Tebas P, Montaner LJ, Ho YC. Inhibition of a Chromatin and Transcription Modulator, SLTM, Increases HIV-1 Reactivation Identified by a CRISPR Inhibition Screen. J Virol. 2022 Jul 13;96(13):e0057722.

• Campbell DM, Dubé K, Cowlings PD, Dionicio P, Tam RM, Agarwal H, Stockman JK, Auerbach JD, Sauceda JA, Conroy AA, Johnson MO. “It comes altogether as one:” perceptions of analytical treatment interruptions and partner protections among racial, ethnic, sex and gender diverse HIV serodifferent couples in the United States. BMC Public Health. 2022 Jul 9;22(1):1317.

• Tembeni B, Sciorillo A, Invernizzi L, Klimkait T, Urda L, Moyo P, Naidoo-Maharaj D, Levitties N, Gyampoh K, Zu G, Yuan Z, Mounzer K, Nkabinde S, Nkabinde M, Gqaleni N, Tietjen I, Montaner LJ, Maharaj V. HPLC-Based Purification and Isolation of Potent Anti-HIV and Latency Reversing Daphnane Diterpenes from the Medicinal Plant Gnidia sericocephala (Thymelaeaceae). Viruses. 2022 Jun 30;14(7):1437.

• Collora JA, Liu R, Pinto-Santini D, Ravindra N, Ganoza C, Lama JR, Alfaro R, Chiarella J, Spudich S, Mounzer K, Tebas P, Montaner LJ, van Dijk D, Duerr A, Ho YC. Single-cell multiomics reveals persistence of HIV-1 in expanded cytotoxic T cell clones. Immunity. 2022 June 14. 55(6): 1013-1031.e.7.

• Dubé K, Eskaf S, Barr L, Palm D, Hogg E, Simoni J, Sugarman J, Brown B, Sauceda JA, Henley L, Deeks SG, Fox L, Gandhi R, Smith DM, Li J. Participant Perspectives and Experiences Following an Intensively Monitored Antiretroviral Pause (IMAP) in the United States: Results from the AIDS Clinical Trials Group (ACTG) A5345 Biomarker Study. AIDS Res Hum Retroviruses. 2022 June. 38(6): 510-517.

• Giron LB, Abdel-Mohsen M. Curr HIV/AIDS Rep. Viral and Host Biomarkers of HIV Remission Post Treatment Interruption. 2022 Jun;19(3):217-233.

• Kreider EF, Bar KJ. HIV-1 Reservoir Persistence and Decay: Implications for Cure Strategies. Curr HIV/AIDS Rep. 2022 Jun;19(3):194-206.

• Gaebler C, Nogueira L, Stoffel E, Oliveira TY, Breton G, Millard KG, Turroja M, Butler A, Ramos V, Seaman MS, Reeves JD, Petroupoulos CJ, Shimeliovich I, Gazumyan A, Jiang CS, Jilg N, Scheid JF, Gandhi R, Walker BD, Sneller MC, Fauci A, Chun TW, Caskey M, Nussenzweig MC. Prolonged viral suppression with anti-HIV-1 antibody therapy. Nature. 2022 Jun;606(7913):368-374.

• Wang M, Sciorillo A, Read S, Divsalar DN, Gyampoh K, Zu G, Yuan Z, Mounzer K, Williams DE, Montaner LJ, de Voogd N, Tietjen I, Andersen RJ. Ansellone J, a Potent in Vitro and ex Vivo HIV-1 Latency Reversal Agent Isolated from a Phorbas sp. Marine Sponge. J Nat Prod. 2022 May 27;85(5):1274-1281.

• Sugawara S, Reeves RK, Jost S. Learning to Be Elite: Lessons From HIV-1 Controllers and Animal Models on Trained Innate Immunity and Virus Suppression. Front Immunol. 2022;13:858383.

• Dubé K, Kanazawa J, Patel H, Louella M, Sylla L, Sheehy J, Dee L, Taylor J, Adair J, Anthony-Gonda K, Dropulić B, Sauceda JA, Peluso MJ, Deeks SG, Simoni J. Ethical and practical considerations for cell and gene therapy toward an HIV cure: findings from a qualitative in-depth interview study in the United States. BMC Med Ethics. 2022 Apr 9;23(1):39

• Prévost J, Richard J, Gasser R, Medjahed H, Kirchhoff F, Hahn BH, Kappes JC, Ochsenbauer C, Duerr R, Finzi A. Detection of the HIV-1 Accessory Proteins Nef and Vpu by Flow Cytometry Represents a New Tool to Study Their Functional Interplay within a Single Infected CD4+ T Cell. J Virol. 2022 Mar 23;96(6):e0192921.

• White JA, Simonetti FR, Beg S, McMyn NF, Dai W, Bachmann N, Lai J, Ford WC, Bunch C, Jones JL, Ribeiro RM, Perelson AS, Siliciano JD, Siliciano RF. Complex decay dynamics of HIV virions, intact and defective proviruses, and 2LTR circles following initiation of antiretroviral therapy. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6): e2120326119.

• Dubé K, Eskaf S, Hastie E, Agarwal H, Henley L, Roebuck C, Carter WB, Dee L, Taylor J, Mapp D, Campbell DM, Villa TJ, Peterson B, Lynn KM, Lalley-Chareczko L, Hiserodt E, Kim S, Rosenbloom D, Evans BR, Anderson M, Hazuda DJ, Shipley L, Bateman K, Howell BJ, Mounzer K, Tebas P, Montaner LJ. Preliminary Acceptability of a Home-Based Peripheral Blood Collection Device for Viral Load Testing in the Context of Analytical Treatment Interruptions in HIV Cure Trials: Results from a Nationwide Survey in the United States. J Pers Med. 2022 Feb 7;12(2): 231.

• Siliciano JD, Siliciano RF. In Vivo Dynamics of the Latent Reservoir for HIV-1: New Insights and Implications for Cure. Annu Rev Pathol. 2022 Jan 24;17:271-294.

• Collora JA, Ho YC. The loud minority: Transcriptionally active HIV-1-infected cells survive, proliferate, and persist. Cell. 2022 Jan 20;185(2):227-229.

• Einkauf KB, Osborn MR, Gao C, Sun W, Sun X, Lian X, Parsons EM, Gladkov GT, Seiger KW, Blackmer JE, Jiang C, Yukl SA, Rosenberg ES, Yu XG, Lichterfeld M. Parallel analysis of transcription, integration, and sequence of single HIV-1 proviruses. Cell. 2022 Jan 20;185(2):266-282.e15.

• Kanazawa J, Gianella S, Concha-Garcia S, Taylor J, Kaytes A, Christensen C, Patel H, Ndukwe S, Rawlings SA, Hendrickx S, Little S, Brown B, Smith D, Dubé K. Ethical and practical considerations for HIV cure-related research at the end-of-life: a qualitative interview and focus group study in the United States. BMC Med Ethics. 2022 Jan 11;23(1):2.

• Turk G, Seiger K, Lian X, Sun W, Parsons EM, Gao C, Rassadkina Y, Polo ML, Czernikier A, Ghiglione Y, Vellicce A, Varriale J, Lai J, Yuki Y, Martin M, Rhodes A, Lewin SR, Walker BD, Carrington M, Siliciano R, Siliciano J, Lichterfeld M, Laufer N, Yu XG. A Possible Sterilizing Cure of HIV-1 Infection Without Stem Cell Transplantation. Ann Intern Med. 2022 Jan;175(1):95-100.

• Dubé K, Kanazawa J, Campbell C, Boone CA, Maragh-Bass AC, Campbell DM, Agosto-Rosario M, Stockman JK, Diallo DD, Poteat T, Johnson M, Saberi P, Sauceda JA. Considerations for Increasing Racial, Ethnic, Gender, and Sexual Diversity in HIV Cure-Related Research with Analytical Treatment Interruptions: A Qualitative Inquiry. AIDS Res Hum Retroviruses. 2022 Jan;38(1):50-63.

• Adeniji OS, Giron LB, Abdel-Mohsen M. Examining the Impact of Galectin-9 on Latent HIV Transcription. Methods Mol Biol. 2022; 2442:463-474.

• Lian X, Gao C, Sun X, Jiang C, Einkauf KB, Seiger KW, Chevalier JM, Yuki Y, Martin M, Hoh R, Peluso MJ, Carrington M, Ruiz-Mateos E, Deeks SG, Rosenberg ES, Walker BD, Lichterfeld M, Yu XG. Signatures of immune selection in intact and defective proviruses distinguish HIV-1 elite controllers. Sci Transl Med.2021 Dec 15;13(624):eabl4097.

• Huang AS, Ramos V, Oliveira TY, Gaebler C, Jankovic M, Nussenzweig MC, Cohn LB. Integration features of intact latent HIV-1 in CD4+ T cell clones contribute to viral persistence. J Exp Med. 2021 Dec 6;218(12): e20211427.

• Adeniji OS, Kuri-Cervantes L, Yu C, Xu Z, Ho M, Chew GM, Shikuma C, Tomescu C, George AF, Roan NR, Ndhlovu LC, Liu Q, Muthumani K, Weiner DB, Betts MR, Xiao H, Abdel-Mohsen M. Siglec-9 defines and restrains a natural killer subpopulation highly cytotoxic to HIV-infected cells. PLoS Pathog. 2021 Nov 11;17(11):e1010034.

• Prévost J, Medjahed H, Vézina D, Chen HC, Hahn BH, Smith AB 3rd, Finzi A. HIV-1 Envelope Glycoproteins Proteolytic Cleavage Protects Infected Cells from ADCC Mediated by Plasma from Infected Individuals. Viruses. 2021 Nov 6;13(11): 2236.

• Dubé K, Kanazawa J, Dee L, Taylor J, Sauceda JA, Gianella S, Smith D, Deeks SG, Peluso MJ. Considerations for designing and implementing combination HIV cure trials: findings from a qualitative in-depth interview study in the United States. AIDS Res Ther. 2021 Oct 18;18(1):75.

• Stone M, Rosenbloom DIS, Bacchetti P, Deng X, Dimapasoc M, Keating S, Bakkour S, Richman DD, Mellors JW, Deeks SG, Lai J, Beg S, Siliciano JD, Pagliuzza A, Chomont N, Lackman-Smith C, Ptak RG, Busch MP. Assessing the Suitability of Next-Generation Viral Outgrowth Assays to Measure Human Immunodeficiency Virus 1 Latent Reservoir Size. J Infect Dis. 2021 Oct 13;224(7):1209-1218.

• Papasavvas E, Azzoni L, Ross BN, Fair M, Howell BJ, Hazuda DJ, Mounzer K, Kostman JR, Tebas P, Montaner LJ. Comparable HIV suppression by pegylated-IFN-α2a or pegylated-IFN-α2b during a 4-week analytical treatment interruption. AIDS. 2021 Oct 1;35(12):2051-2054.

• Bosso M, Stürzel CM, Kmiec D, Badarinarayan SS, Braun E, Ito J, Sato K, Hahn BH, Sparrer KMJ, Sauter D, Kirchhoff F. An additional NF-κB site allows HIV-1 subtype C to evade restriction by nuclear PYHIN proteins. Cell Rep. 2021 Sep 21;36(12):109735